Peptide Therapy

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What Are Peptides?

In short, peptides are amino acid chains that directly link to signals sent between cells in your body. Sounds confusing, doesn’t it? Their real job is to help your body use its own innate healing abilities to move toward optimal health.
These strings of amino acids can contain anywhere from 2-40 individual amino acids. These are quite a bit smaller than many regular proteins in the body, making them easy for your system to process and utilize.

Each peptide has its own unique function. For example: some might act as hormones, while others work as neurotransmitters. Some may even have direct interactions with the body as a response to activities you perform or even something you eat.
Peptides play a major role in how your body responds to diet and exercise. If issues of fatigue, endurance, poor recovery, or injury and healing are concerns, peptides can accelerate improvements.

Adequate peptide levels are imperative for:

performing at optimal levels.
BPC-1157 – Pentadecapeptide
Healing Therapy

AOD-9604

AOD-9604 is a synthetic peptide that is a modified fragment of human growth hormone. It was developed to specifically target fat metabolism, aiming to promote fat breakdown and reduce new fat formation, without stimulating growth or affecting IGF-1 levels, which are associated with full-length growth hormone.

Benefits include:

\Targeted Fat Reduction: May help reduce fat in specific areas like the abdomen and thighs (Human Study).
\Neutral on Glucose: Does not appear to negatively impact insulin or carbohydrate metabolism (Human Study).
\Direct Fat Metabolism: May stimulate fat breakdown without affecting appetite (Animal Study).
\No IGF-1 Effects: Does not promote growth or exhibit pro-diabetic effects (Human Study).
\Glucose Handling: Some evidence suggests improved glucose processing in patients with impaired glucose tolerance (Human Study).
\Oral Bioavailability: Can be absorbed orally, with tissue distribution similar to intravenous administration (Animal Study).
\Safety Profile: Demonstrated safety comparable to placebo in human clinical trials (Human Study).
\Low Immunogenicity: Did not lead to antibody formation in studies up to 24 weeks (Human Study).
\Cartilage Support: Preclinical data suggest potential benefits for cartilage health (Animal Study).
\Lean Mass Preservation: Observed fat loss without a decrease in muscle mass (Animal Study).

BPC-157

BPC-157 is a short chain of amino acids, a peptide naturally found in gastric juice. It’s often called a “body protection compound” due to its wide-ranging potential benefits, particularly in tissue repair and inflammation modulation.

Benefits include:

\Tissue Regeneration: May help speed up recovery of muscles, tendons, and ligaments after injury (Animal Study).
\Wound Healing: May promote faster closure of wounds and ulcers (Animal Study).
\Anti-inflammatory Effects: May reduce inflammation in various tissues (Animal Study).
\Gastrointestinal Protection: May help protect and heal the lining of the stomach and intestines (Animal Study).
\Pain Reduction: May lessen discomfort associated with injuries (Animal Study).
\Nerve Repair: May support the repair and regeneration of damaged nerves (Animal Study).
\Bone Healing: May accelerate the repair of bone fractures (Animal Study).

BPC-157 + TB-500

The BPC-157/TB-500 blend combines two regenerative peptides that appear to work better together than alone.

Benefits include:

\Musculoskeletal Repair: May support faster healing of tendons, ligaments, muscle, and bone (Animal Study).
\Wound Healing: May improve collagen formation, blood vessel growth, and wound closure (Animal Study).
\Fibroblast Migration: May enhance movement of repair cells to injury sites (Lab Study).
\Growth hormone receptor activity: May boost receptor expression in tendon cells (Lab Study).
\Cardiac protection: May support repair of heart tissue after injury (Animal Study).
\Neuroprotection: May improve recovery after brain injury or stroke (Animal Study).
\Muscle regeneration: May aid recovery in muscle-wasting conditions (Animal Study).
\Systemic healing: Effects sometimes seen in distant tissues beyond the injection site (Animal Study).
\Metabolic effects: May improve insulin sensitivity and glucose balance (Animal Study).

Cagrilintide / Retatrutide

The Cagrilintide / Retatrutide Combination provides a dual-mechanism strategy for weight management and metabolic health.

Cagrilintide – a long-acting amylin analog (half-life ~165 hours) that enhances satiety, slows gastric emptying, and suppresses postprandial glucagon via brainstem amylin receptor activation. 

Retatrutide – a triple agonist of GLP-1, GIP, and glucagon receptors (half-life ~6 days), promoting insulin secretion, hepatic fat oxidation, appetite suppression, and energy expenditure.

Benefits include:

\Superior Weight Reduction: Clinical data suggest additive benefit vs monotherapy (Cagrilintide ~10.8%; Retatrutide up to 24%).
\Dual Appetite Suppression: Amylin-mediated satiety + GLP-1/GIP/glucagon receptor effects.
\Improved Glucose Regulation: Insulinotropic effects of Retatrutide + glucagon suppression from Cagrilintide.
\Increased Energy Expenditure: Enhanced fatty acid oxidation and thermogenesis.
\Gastric Emptying Delay: promoting satiety and postprandial glucose control.
\Metabolic Flexibility: Enhanced fat utilization and energy partitioning.
\Liver Fat Reduction: Up to 80% reduction in NAFLD markers with Retatrutide, supported by amylin synergy.
\Cardiovascular Benefit: Potential improvements in blood pressure, lipids, and inflammation.
\Hormonal Synergy: Targeting multiple endocrine pathways for comprehensive metabolic support.
\Potential Diabetes Remission: Through insulin sensitization, glucagon suppression, and beta-cell support.

CagriSema (Cagrilintide + Semaglutide)

CagriSema is a co-formulated combination therapy containing 2.4 mg each of Cagrilintide (a long-acting amylin analog) and Semaglutide (a GLP-1 receptor agonist), administered as a single weekly subcutaneous injection. This dual-hormone approach targets obesity and type 2 diabetes through complementary mechanisms.

Benefits include:

\Weight Loss Superiority: Up to 22.7% mean bodyweight reduction at 68 weeks.
\High Responder Rate: ~60% of patients achieved ≥20% weight loss.
\Glycemic Control: Mean HbA1c reduction of 2.07%; 74% achieved HbA1c ≤6.5%.
\Dual Appetite Suppression: Targeting both homeostatic and hedonic eating pathways.
\Cardiovascular Benefits: Reductions in systolic blood pressure and improvements in lipid profile.
\Diabetes Remission Potential: Durable improvements in weight and glycemic indices.
\Favorable Tolerability: Mostly GI-related adverse events with relatively low discontinuation.
\Flexible Dosing: Clinically meaningful weight loss achieved even below maximum dosing levels.

Cagrilintide / Tirzepatide

The Cagrilintide + Tirzepatide Combination represents a novel dual-pathway strategy for obesity and type 2 diabetes management. It integrates Cagrilintide, a long-acting amylin analog, with Tirzepatide, a dual GIP/GLP-1 receptor agonist, to deliver complementary appetite suppression, metabolic regulation, and glycemic control.

Benefits include:

”Enhanced
\Superior Glycemic Control: ≥2.0% HbA1c reduction; higher rates of normoglycemia.
\Dual Glucagon Suppression: Reduced hepatic glucose output from both amylin and incretin action.
\Increased Energy Expenditure: Tirzepatide boosts fat oxidation; Cagrilintide reduces intake.
\Synergistic Gastric Motility Slowing: Prolongs satiety and stabilizes postprandial glucose.
\Metabolic Flexibility: Enhanced lipid oxidation and ketone production support cardiometabolic health.
\Cardiovascular Benefits: Reductions in systolic BP, LDL cholesterol, and inflammatory markers.
\Diabetes Remission Potential: Weight reduction and insulin sensitization support remission.
\Improved Tolerability: Smoother PK profile may reduce GI-related adverse events.
\Optimized Adherence: Simplified once-weekly co-administration.

CJC-1295 + Ipamorelin

CJC-1295 + Ipamorelin is a combination of two peptides designed to naturally boost the body’s own growth hormone (GH) production and its related effects, particularly IGF-1. CJC-1295 is a long-acting compound that binds to albumin in the blood, allowing it to stay in the system for about 6-8 days after a single injection, leading to sustained increases in GH and IGF-1.

Benefits include:

\Enhanced Growth Hormone Levels: Leads to significant and sustained increases in GH and IGF-1, with added natural growth hormone pulses. (Human Study).
\Improved Body Composition: May help increase lean muscle mass and reduce body fat by boosting protein building and fat breakdown. (Human Study).
\Faster Recovery: Supports the body's ability to heal and repair tissues, including collagen, after exercise or injury. (Human Study).
\Better Sleep: May improve sleep quality, particularly deeper sleep cycles, and enhance overall well-being. (Human Study).
\Reduced Side Effects: Ipamorelin specifically targets GH release with minimal impact on cortisol or prolactin, leading to a better safety profile. (Lab Study).
\Convenient Dosing: CJC-1295's long-lasting effect allows for infrequent dosing, often once or twice a week. (Human Study).
\Trackable Results: Changes in certain blood markers, including IGF-1, can be used to monitor the effectiveness of CJC-1295. (Human Study).

Delta Sleep-Inducing Peptide

Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring nonapeptide first identified for its role in regulating sleep architecture.

Benefits include:

\Enhanced Sleep Efficiency: Up to 59% increase in total sleep duration.
\Withdrawal Management: 97% success in opioid withdrawal; 87% success in alcohol withdrawal.
\Pain Relief: Reduction in migraines, psychogenic pain, and chronic pain syndromes.
\Improved Sleep Quality: Increases restorative slow-wave (stage 4) sleep.
\Insomnia Treatment: Decreases sleep onset latency; sustained benefits in chronic cases.
\Stress Reduction: Demonstrated anxiolytic effects and improved stress resilience.
\Neuroprotection: Reduces glutamate excitotoxicity, supporting brain health.
\No Next-day Sedation: Preserves cognitive performance upon waking.
\Circadian Rhythm Support: May help normalize disrupted sleep-wake cycles.

Epithalon

Epithalon is a synthetic tetrapeptide that mimics epithalamin, a natural peptide produced by the pineal gland.

Benefits include:

\Telomere Elongation: 33.3% average increase in human fibroblasts (Lab Study).
\Mortality Reduction: 1.6–4.1 fold decreased mortality in elderly populations (Human Study).
\Cardiovascular Protection: 50% reduction in cardiovascular mortality over 12 years (Human Study).
\Melatonin Restoration: 3-fold increase in nighttime melatonin levels in aged subjects (Human Study).
\Visual Improvement: 90% positive response in retinitis pigmentosa (Human Study).
\Tumor Suppression: 6-fold reduction in spontaneous tumor development in cancer-prone mice (Animal Study).
\Anti-inflammatory Effects: Reduced TNF-α and IL-6; improved T-cell function (Lab Study).
\Cellular Rejuvenation: Extended replicative lifespan in cultured cells from 34 to 44 passages (Lab Study).
\Antioxidant Enhancement: 36% increase in total antioxidant capacity and reduced reactive oxygen species (Lab Study).

GHK-CU

GHK-Cu is a naturally occurring tripeptide-copper complex, originally isolated from human plasma. Circulating levels decline with age—from ~200 ng/mL at age 20 to ~80 ng/mL by age 60—correlating with decreased regenerative capacity.

Benefits include:

\Enhanced Wound Healing: 64.5% reduction in wound size versus controls.
\Skin Rejuvenation: 55.8% clinical reduction in wrinkle volume.
\Collagen Synthesis: Stimulates at nanomolar concentrations in fibroblasts.
\Antioxidant Activity: Superior hydroxyl radical scavenging compared to glutathione.
\DNA Repair: Upregulates 47 genes involved in DNA repair.
\Anti-inflammatory: Reduces TNF-α-induced IL-6 secretion in fibroblasts.
\Cognitive Support: Improves spatial navigation in aged murine models.
\Systemic Tissue Regeneration: Benefits reported across multiple organ systems.

Glow

The GLOW Stack combines three regenerative peptides—BPC-157, TB-500, and GHK-Cu—to target multiple aspects of healing and tissue health.

Benefits include:

\Angiogenesis: May improve blood vessel formation and circulation (Animal Study).
\Accelerated Tissue Repair: May support faster healing of tendon, ligament, muscle, and skin injuries (Animal Study).
\Anti-inflammatory Effects: May reduce oxidative stress and inflammatory cytokines (Animal Study).
\Collagen Synthesis: May stimulate type I/III collagen for stronger, more elastic skin (Lab Study).
\Cellular Migration & Remodeling: May enhance actin-driven cell movement and matrix repair (Animal Study).
\Reduced Scarring: May decrease fibrosis and improve tissue architecture (Animal Study).
\Antimicrobial Protection: May aid wound healing by supporting barrier function (Lab Study).
\Gut Support: May improve intestinal lining integrity and nutrient absorption (Animal Study).
\Skin Rejuvenation: May improve skin firmness, density, and reduce sun damage (Human Study).
\Enhanced Recovery: May shorten healing time after surgery or injury (Animal Study).

IGF-1LR3

IGF-1 LR3 is a synthetic analog of IGF-1, engineered with:

– Arginine substitution at position 3 (Arg3)
– Extended peptide sequence

Benefits include:

\Muscle Growth: Increases lean body mass via satellite cell proliferation and differentiation.
\Recovery & Regeneration: Accelerates repair of skeletal muscle, tendons, ligaments, and other tissues post-injury or exercise.
\Protein Synthesis: Enhances anabolic processes for faster muscle development.
\ Fat Metabolism: Improves glucose utilization and promotes fat oxidation.
\Insulin Sensitivity: Enhances insulin action and glucose uptake in tissues.
\Bone Health: Supports bone density and skeletal tissue strength.
\Cardiovascular Health: Promotes angiogenesis and endothelial function, aiding vascular repair.

Ipamorelin

Ipamorelin is a synthetic pentapeptide and highly selective growth hormone secretagogue (GHS) that acts specifically on the GHS-R1a receptor. Unlike other GHRPs, it selectively stimulates pituitary GH release without affecting other hormones like ACTH, cortisol, prolactin, FSH, LH, or TSH, even at doses up to 200× the ED50 for GH.

Benefits include:

\Selective GH Stimulation: Stimulates GH without raising cortisol, ACTH, prolactin, or other pituitary hormones.
\Physiological GH Release: Maintains natural pulsatile patterns; mimics endogenous GH cycles.
\Reduced Injection Frequency: Longer half-life allows fewer injections compared to GHRP-2 or GHRP-6.
\Safety Profile: Mild, transient side effects; lower risk than non-selective GHRPs.
\Tissue Repair & Recovery: GH-mediated pathways may enhance wound healing, recovery from injury, and anabolic signaling.
\Body Composition: Potential benefits via GH/IGF-1 pathways (lean mass, fat metabolism).
\Sleep Architecture: May improve slow-wave sleep indirectly through GH release (animal data; limited human studies).
\Metabolic Effects: Potential glucose and lipid metabolism benefits via GH pathways (preclinical/animal data).

KPV

KPV (Lysine-Proline-Valine) is a naturally occurring tripeptide derived from the C-terminal sequence of α-melanocyte-stimulating hormone (α-MSH). Unlike other melanocortin peptides, KPV exhibits potent anti-inflammatory effects independent of melanocortin receptors.

Benefits include:

\Anti-Inflammatory: 35-50% reduction in pro-inflammatory cytokines in human epithelial cells; inhibits NF-κB signaling.
\Intestinal Health: 50% reduction in myeloperoxidase activity; reduces IBD symptoms; protects against colitis-associated cancer via PepT1 pathway.
\Wound Healing & Tissue Repair: 2× faster epithelial barrier restoration; improved collagen organization and angiogenesis.
\Antimicrobial Activity: Effective against S. aureus and C. albicans.
\Drug Delivery Advantages: 35-fold enhanced transdermal penetration with iontophoresis; orally targeted delivery via functionalized nanoparticles.
\Safety Profile: Avoids corticosteroid-like immunosuppression; effective in patients with melanocortin receptor variants.

MOTS-C

MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA Type-C) is a 16-amino acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA gene.

It represents a novel mechanism of mitochondrial-nuclear communication, linking cellular energy status to gene expression.

Benefits include:

\Insulin Sensitivity: 30% increase in glucose infusion rate (Cell Metabolism, 2015).
\Exercise Mimetic: Boosts MOTS-C post-exercise to improve metabolic adaptations (Nature Communications, 2021).
\Cardiac Function: Enhanced systolic function and cardiac output (Cell Metabolism, 2018).
\Physical Performance: Increases lifespan and maximal performance in preclinical models.
\Obesity Prevention: Improves energy expenditure and glucose utilization (PMC Review, 2022).
\Bone Preservation: Prevents bone loss and enhances mineral density.
\Cognitive Benefits: Reduces pro-inflammatory cytokines, supports memory.
\Anti-inflammatory: Increases IL-10, reduces systemic inflammation.
\Autoimmune Diabetes Protection: Enhances regulatory T cell activity.
\Thermogenesis: Activates brown adipose tissue and upregulates thermogenic genes.

NAD+

NAD+ (nicotinamide adenine dinucleotide) is a vital coenzyme found in all living cells that plays a central role in energy production, DNA repair, and overall cell health. It acts as a critical partner for enzymes involved in metabolism, helping to generate ATP, the body’s main energy currency.

Benefits include:

\Improved Energy: Higher NAD+ levels support better mitochondrial function, which can improve energy production and fat burning. (Lab Study).
\DNA Repair: NAD+ is crucial for enzymes that help repair damaged DNA, supporting genetic stability. (Lab Study).
\Cellular Resilience: Restoring NAD+ may help cells better handle stress and reduce signs of aging. (Lab Study).
\Metabolic Health: NAD+ can improve how the body uses glucose and fats, potentially enhancing insulin sensitivity. (Lab Study).
\Brain Protection: Maintaining NAD+ levels may help protect brain cells from injury and support nerve health. (Lab Study).
\Reduced Inflammation: NAD+ can influence immune cells and reduce inflammatory responses in the body. (Lab Study).
\Increased NAD+ Levels: Oral forms of NAD+ precursors have been shown to significantly raise NAD+ levels in human blood. (Human Study).
\Good Safety Profile: Studies indicate that NAD+ precursors are generally well-toler

PT-141

PT-141 is a synthetic peptide derived from melanocortin hormones. It acts as a melanocortin receptor agonist, primarily targeting MC3R and MC4R in the central nervous system. Unlike PDE-5 inhibitors (e.g., Viagra), PT-141 enhances sexual function via neurological pathways rather than directly affecting vascular function. It is administered subcutaneously and is indicated for hypoactive sexual desire disorder (HSDD) and other forms of sexual dysfunction.

Benefits include:

\Sexual Desire: Increases libido and sexual arousal in men and women.
\Erectile Function: Supports enhanced sexual performance via CNS activation.
\Aphrodisiac Effect: Heightens sexual motivation through melanocortin receptor pathways.
\Non-vascular Mechanism: Effective even for individuals with vascular-related sexual dysfunction.
\Anxiety Reduction: May reduce performance anxiety and improve confidence during intimacy.
\Rapid Onset: Effects observed within ~30 minutes after subcutaneous administration.
\Safety Profile: Minimal systemic side effects; does not significantly affect BP or cardiac function.

Retatrutide

Retatrutide is a multi-receptor peptide agonist targeting GLP-1, GIP, and glucagon receptors, developed for the treatment of obesity and type 2 diabetes.

Benefits include:

\Weight Loss: Up to 24% body weight reduction in clinical trials; targets visceral fat.
\Glycemic Control: HbA1c reduction up to 2.2%; improves glucose homeostasis and insulin sensitivity.
\Energy Expenditure: Promotes thermogenesis and fatty acid oxidation through glucagon receptor activity.
\Appetite Regulation: Enhanced satiety and reduced caloric intake via GLP-1 and GIP pathways.
\Cardiovascular Health: Reduces triglycerides, improves lipid profile, lowers systolic blood pressure.
\Fat Loss & Body Composition: Preferential visceral fat reduction; maintains lean mass.
\Metabolic Flexibility: Optimizes glucose and lipid metabolism for overall metabolic health.
\Sustained Efficacy: Once-weekly dosing supports long-term adherence and durable metabolic effects.

Semaglutide

Semaglutide is a synthetic GLP-1 receptor agonist with 94% homology to endogenous GLP-1. It has been structurally modified to resist dipeptidyl peptidase-4 (DPP-4) degradation and to enhance albumin binding, extending its half-life to approximately 165 hours. This enables once-weekly subcutaneous dosing (Ozempic® for type 2 diabetes, Wegovy® for obesity) or daily oral dosing (Rybelsus®).

Benefits include:

\Weight Loss: Mean 15.2% body weight reduction; 40% losing ≥20%.
\Cardiovascular Protection: 26% reduction in major CV events; improved endothelial function.
\Appetite Suppression: Central GLP-1 receptor activation reduces caloric intake.
\Insulin Sensitivity: Improved HOMA-IR; maintains β-cell function.
\Convenient Dosing: Once-weekly subcutaneous or daily oral administration.
\Multi-Organ Benefits: Kidney, liver, and potential neuroprotection.
\Safety Profile: Mild-to-moderate GI side effects, usually resolving with dose titration.
\Sustained Efficacy: Long-term weight and glycemic control maintained for up to 2 years.

Sermorelin

Sermorelin is a peptide that works by mimicking the natural growth hormone-releasing hormone (GHRH) produced in the body. It directly stimulates the pituitary gland to increase its own production and release of growth hormone (GH) in a natural, pulsatile way.

Benefits include:

\Natural GH Boost: Increases your body's own growth hormone and IGF-1 levels while maintaining natural feedback control. (Human Study).
\Supports Pituitary Health: Helps maintain the pituitary gland's ability to produce growth hormone long-term. (Lab Study).
\Body Composition Improvements: May help increase lean body mass and reduce fat, consistent with growth hormone's effects. (Human Study).
\Better Sleep and Vitality: Enhancing natural nighttime GH pulses may lead to improved sleep and overall well-being. (Human Study).
\Diagnostic Tool: Can be used to assess the pituitary gland's capacity to release growth hormone. (Human Study).
\Potentially Lower Risk: May carry a lower theoretical risk of abnormal cell growth compared to direct GH injections because it works within the body's natural feedback limits. (Human Study).
\Flexible Dosing: Its short action allows for precise timing of doses to align with natural hormone rhythms and individual needs. (Lab Study).

TB-500

TB-500 is a synthetic peptide based on a key part of thymosin beta-4 (Tβ4), a protein naturally found in the body that is important for healing and tissue repair. Tβ4 works by interacting with actin, a protein crucial for cell movement and structure. This interaction helps cells move quickly, reshape their internal framework, and repair damaged tissues.

Benefits include:

\Accelerated Wound Healing: May help speed up the closing of wounds and the regrowth of skin and tissue layers. (Animal Study).
\Improved Blood Flow: May promote the growth of new blood vessels and enhance circulation in injured areas. (Lab Study).
\Reduced Inflammation: May help decrease inflammatory signals and improve the healing environment. (Animal Study).
\Soft Tissue Repair: May support the healing and functional recovery of tendons, ligaments, and muscles after injury. (Animal Study).
\Heart Tissue Support: May help protect and remodel heart tissue following injury. (Animal Study).
\Nerve Support: May promote nerve growth and functional improvement after brain or nerve injury. (Animal Study).
\Ocular Healing: May aid in the healing of the cornea and other eye surfaces. (Animal Study).
\Targeted Delivery: May distribute throughout the body and concentrate at sites of injury where repair cells are needed. (Animal Study)

Tesamorelin

Tesamorelin is a synthetic form of growth hormone-releasing hormone (GHRH) designed to stimulate the body’s own production of growth hormone (GH) and a related hormone called IGF-1. It’s modified to last longer in the body, allowing for once-daily injections to effectively boost natural GH pulses.

Benefits include:

\Significant Visceral Fat Reduction: Clinically proven to reduce deep abdominal fat. (Human Study).
\Improved Cholesterol and Triglycerides: Positively affects blood fat levels, including triglycerides and cholesterol ratios. (Human Study).
\Maintains Body Shape: Reduces abdominal fat without causing significant loss of fat under the skin, which can improve body image. (Human Study).
\Liver Health Benefits: In HIV-positive individuals with fatty liver disease, it can decrease liver fat and reduce inflammation. (Human Study).
\No Worsening of Insulin Sensitivity: Does not appear to negatively impact blood sugar control, even with increased growth hormone activity. (Human Study).
\Long-Term Effectiveness: The fat-reducing effects can be maintained with continued treatment. (Human Study).
\Natural GH Stimulation: Encourages the body to release its own growth hormone in a natural, pulsed manner, which may have fewer off-target risks compared to direct GH injections. (Lab Study).
\Modern Formulations Available: Newer, concentrated versions are being developed to support its use. (Regulatory Document).

Tirzepatide

Tirzepatide is a dual incretin receptor agonist designed to optimize metabolic outcomes through:
1. GIP receptor (GIPR) activation
– Enhances glucose-dependent insulin secretion via cAMP/PKA pathways
– Stimulates β-cell proliferation and reduces apoptosis
– Contributes to appetite suppression without significant nausea
2. GLP-1 receptor (GLP-1R) activation
– Stimulates insulin release and suppresses glucagon secretion
– Delays gastric emptying
– Provides central appetite regulation
– Exhibits biased signaling favoring cAMP over β-arrestin recruitment → sustained receptor expression and enhanced insulin secretory capacity

Benefits include:

\Weight Loss: Up to 22.5% reduction in body weight.
\Glycemic Control: HbA1c reductions of 1.87–2.58%; up to 62.4% achieve normoglycemia.
\Cardiometabolic Risk: Reduced blood pressure, triglycerides, and inflammatory markers.
\Hypoglycemia Risk: Fewer episodes compared to insulin therapies.
\Insulin Sensitivity: Improved metabolic function independent of weight loss.
\Convenient Dosing: Once-weekly injection; high adherence.
\GI Tolerability: Low gastrointestinal side effects; discontinuation rates 4.3–7.1%.

HEALING Therapy

Old Injury? New Injury?

BPC-157 has been shown to accelerate the body’s natural healing processes by increasing the activity of the body’s growth hormone receptor. This peptide can be very useful to athletes or just the average person who has daily aches or injury.

Overuse of our body can cause muscle, tendon and ligament issues that affect our daily life. The addition of BPC-157 can help heal sore knees, pulled hamstring or sprained ankle.

BENEFITS REPORTED:

ACCELERATED HEALING OF CONNECTIVE TISSUES, MUSCLE, AND JOINT DAMAGE
IMPROVEMENT IN DIGESTIVE FUNCTION
GUT PROTECTION
CALCIUM AND MAGNESIUM BALANCE
BETTER MENTAL HEALTH
IMPROVED BLOOD PRESSURE
STABILITY OF BLOOD PRESSURE

what are the benefits of sermorelin

If your are looking for a way to slow the aging process and replace whta has diminished over time from the natural aging process. Sermorelin offers many benefits including: